Intraocular Lymphoma: Ten Points Every Ophthalmologist Should Know
1. Epidemiology of Intraocular Lymphoma: Intraocular Lymphoma is a rare malignancy accounting for 0.01% of ophthalmic conditions. The term includes primary intraocular lymphoma (PIOL) with or without primary central nervous system lymphoma (PCNSL). 1 Majority of the patients with lymphoma are over 50 years of age. 2 2. Presentations and Potential for Misdiagnosis of Intraocular Lymphoma: PIOL has ...Read More
Ten Tenets Every Ophthalmologist should know about Collaborative Ocular TB Study (COTS)
“Ocular tuberculosis, a disease that we fear, Stealthily attacks the eyes, year after year. In the dark and quiet, it spreads its deadly grime, Causing pain and inflammation, and a loss of sight sometimes. Choroidal TB is the commonest sight, With serpiginous-like choroiditis, it takes its flight. Retinal vasculitis too, causes so much pain, Ocular tuberculosis, an insidious foe, it will remain. B...Read More
HLA-B27 associated Acute Anterior Uveitis
Introduction Acute anterior uveitis (AAU) results from a breakdown of the blood-aqueous barrier and acute inflammation of the iris and ciliary body. It is the most common form of uveitis encountered the world over. Keratic precipitates (KPs) are characteristic of AAU and represent inflammatory cells that deposit on the corneal endothelium due to the upregulation of adhesion molecules in response t...Read More
Introduction: Toxoplasmosis is the most common cause of posterior uveitis in the world, accounting for over 80% of the cases in some regions[1-5]. For many years, ocular toxoplasmosis was considered to be the result of the recurrence of the congenital form of the disease [6]. However, it is recently believed that acquired infections might be a more important cause of ocular diseases than congenita...Read More
Human immunodeficiency virus (HIV) disease is a pandemic of global concern, not only due to serious health issues affecting all organs of the body but also due to its huge economic burden.(1) The diagnosis is often associated with social stigma that includes changing sexual practices, lack of availability of a vaccine and the chronicity of the disease requiring lifelong treatment.(2) The disease r...Read More
Viral uveitis has myriad presentations. They may present as anterior uveitis, intermediate uveitis, acute retinal necrosis (ARN), progressive outer retinal necrosis (PORN) and neuroretinitis. The causative viruses mainly include herpes group of viruses and human immunodeficiency virus (HIV). Other DNA viruses which cause uveitis are poxviruses, adenoviruses especially those that produce epidemic k...Read More
Eales Disease: Current Concepts in Etiopathogenesis and Management
Introduction Eales’ disease is an idiopathic retinal periphlebitis that primarily affects the peripheral retina in young adults. Eales’ disease was first described by Henry Eales, a British ophthalmologist, in 1880 and 1882.1,2 He found it in seven young, male patients ranging in age from 14 to 29 years with recurrent vitreous hemorrhage. In addition, these patients had history of headache, variat...Read More
Malarial Retinopathy: A Diagnostic Clue
Introduction Malaria is the most important of parasitic diseases of humans and remains today, as it has been for centuries a large burden on tropical communities. Cerebral malaria is the most important complication of falciparum malaria and also the leading cause of death in malaria 1. It is defined as an acute, symmetric encephalopathy associated with sequestration of parasite-infected erythrocyt...Read More
Seasonal Hyperacute Panuveitis (SHAPU)
Introduction: Seasonal Hyperacute Panuveitis (SHAPU) is a mysterious eye disease with grave prognosis, reported only from Nepal. Though it was reported for the first time in 1975,1-3 no definite etiopathogenesis has been established to date. It occurs as an outbreak in certain regions of Nepal in a cyclical pattern during the autumn season and peaks during the winter season (August–December) only ...Read More
Introduction: Macular edema is defined as swelling of the layers of neurosensory retina within the macula. Cystoid macular edema (CME) is a subtype of macular edema characterized by extracellular accumulation of fluid within the outer plexiform layer of the retina in the form of intraretinal cyst. It is known as one of the complications, that develops consequent to a final common pathway in divers...Read More