Introduction: Toxoplasmosis is the most common cause of posterior uveitis in the world, accounting for over 80% of the cases in some regions[1-5]. For many years, ocular toxoplasmosis was considered to be the result of the recurrence of the congenital form of the disease [6]. However, it is recently believed that acquired infections might be a more important cause of ocular diseases than congenita...Read More
Uvea and Intraocular Inflammation
Human immunodeficiency virus (HIV) disease is a pandemic of global concern, not only due to serious health issues affecting all organs of the body but also due to its huge economic burden.(1) The diagnosis is often associated with social stigma that includes changing sexual practices, lack of availability of a vaccine and the chronicity of the disease requiring lifelong treatment.(2) The disease r...Read More
Ten Points One Must Know on Toxic Anterior Segment Syndrome (TASS)
TASS is an uncommon, non-infectious condition causing severe inflammation of the anterior segment structures without vitreous involvement [1],[2],[5]. The name TASS was coined by Monson and colleagues in 1992 [1],[3]. It is usually associated with phacoemulsification surgery but can also happen after procedures like penetrating keratoplasty, descemet stripping automated endothelial keratoplasty, d...Read More
i-File: Vogt-Koyanagi - Harada disease
Brief Scenario of the case: A 25 year-old-female, resident of Rajasthan presented to us with the chief complaints of diminution of vision in the right eye for a period of 3 days and redness with mild pain in both eyes for one month. History of Present Illness: The patient was apparently well 3 days back when she started to develop diminution of vision in her right eye. She had mild pain and rednes...Read More
Question A healthy 26-year-male presented with sudden onset diminution of vision in OS of 1-week duration. The loss of vision was not associated with any trauma, pain, redness. No history of flashes. No previous history of a similar episode. On examination BCVA OD: 6/9 N6; OS: HM. Anterior segment unremarkable OU. Fundus: OD: as depicted in the fundus and FFA, OS: had a dense vitreous hemorrhage W...Read More
Introduction Intraocular lymphoma, a great non-infective masquerader occurs intraocularly in either the vitreoretinal( primary vitreoretinal lymphoma PVRL)) or in the uveal space( primary choroidal, iris lymphoma). By definition, PVRL denotes the presence of pathology limited to vitreoretinal space without its occurrence in the central nervous system. The term ‘primary’ is however controversial as...Read More
Viral uveitis has myriad presentations. They may present as anterior uveitis, intermediate uveitis, acute retinal necrosis (ARN), progressive outer retinal necrosis (PORN) and neuroretinitis. The causative viruses mainly include herpes group of viruses and human immunodeficiency virus (HIV). Other DNA viruses which cause uveitis are poxviruses, adenoviruses especially those that produce epidemic k...Read More
Eales Disease: Current Concepts in Etiopathogenesis and Management
Introduction Eales’ disease is an idiopathic retinal periphlebitis that primarily affects the peripheral retina in young adults. Eales’ disease was first described by Henry Eales, a British ophthalmologist, in 1880 and 1882.1,2 He found it in seven young, male patients ranging in age from 14 to 29 years with recurrent vitreous hemorrhage. In addition, these patients had history of headache, variat...Read More
Malarial Retinopathy: A Diagnostic Clue
Introduction Malaria is the most important of parasitic diseases of humans and remains today, as it has been for centuries a large burden on tropical communities. Cerebral malaria is the most important complication of falciparum malaria and also the leading cause of death in malaria 1. It is defined as an acute, symmetric encephalopathy associated with sequestration of parasite-infected erythrocyt...Read More
Seasonal Hyperacute Panuveitis (SHAPU)
Introduction: Seasonal Hyperacute Panuveitis (SHAPU) is a mysterious eye disease with grave prognosis, reported only from Nepal. Though it was reported for the first time in 1975,1-3 no definite etiopathogenesis has been established to date. It occurs as an outbreak in certain regions of Nepal in a cyclical pattern during the autumn season and peaks during the winter season (August–December) only ...Read More