Simple Limbal Epithelial Transplantation: A Review
I. Introduction The cornea is lined by non-keratinized, stratified squamous epithelium. At the limbus, there is a gradual transition of these cells to non-keratinized, stratified columnar epithelial cells, along with mucin-secreting goblet cells, forming the conjunctival epithelium. The corneoscleral limbus lies between these two epithelia in a healthy eye. The limbus contains palisades of Vogt, t...Read More
Introduction Allergic eye disease (AED) is a common problem, owing to the fact that the eye is the first organ to encounter environmental allergens. It has been reported to affect 20% of the population worldwide1, 2. Allergic eye disease is found to be on the rise in line with other atopic diseases like asthma, due to environmental reasons. Classification of Allergic Eye Diseases 1, 4 1. Allergic ...Read More
Peripheral Ulcerative Keratitis
Peripheral ulcerative keratitis (PUK) is a form of ocular inflammation that involves the peripheral portion of cornea and may be associated with systemic conditions such as Rheumatoid Arthritis(RA), Wegener’s Granulomatosis(WG), and other systemic conditions. It is a potentially devastating disorder consisting of a crescent-shaped destructive inflammation at the margin of corneal stroma that is as...Read More
WHAT IS CORNEAL TOPOGRAPHY? Corneal topography is the study of the shape of the corneal surface. Traditionally, such measurements were limited to the near-spherical central portion of the anterior corneal surface. With the advent of corneal refractive procedures, the necessity to study the more peripheral parts of the cornea and to understand better the optics of both the anterior and posterior co...Read More
Chemical Injuries of Eye - An Update.
Introduction It is very frequent to encounter chemical injury in our routine ophthalmic practice. Most of the chemical injuries are minor, which heal without any squeal. Most are acids and alkalis. Alkali injuries are more common (nearly twice) than acids and are more severe in nature. It is of utmost importance to recognize the nature of chemicals for treating such patients. Here, we review the c...Read More
Cornea Edema : Ready Reckoner for the Post Graduates
Corneal edema is defined as the increase in the thickness of cornea due to the accumulation of extracellular fluid in epithelium and stroma resulting in loss of corneal transparency. Pathophysiology: Cornea remains in a relatively dehydrated state maintaining a 78% hydration level. Corneal hydration depends on 5 factors. 1. Stromal swelling pressure (SP) This is the tendency of stroma to swell due...Read More
Acanthamoeba Keratitis: A review for the Postgraduates
Eye diseases affecting the cornea are a major cause of blindness worldwide. Among different infectious agents, bacteria, fungi, viruses and protozoans may be causes of keratitis. This article is about the keratitis caused by protozoa. Three amoebic parasites are thought to be significant to human disease, entamoeba which is responsible for amoebic dysenter, naegleria which causes amoebic meningoen...Read More
Fungal Keratitis: A Review for the Post-Graduates
Introduction Fungal or mycotic keratitis is a leading cause of ocular morbidity, opacification and preventable blindness.1 The approximate annual incidence of fungal keratitis in India is said to be 11.3/10,000 population.2 Frequently it is caused by filamentous fungi (Aspergillus, Fusarium, Curvularia) in the tropical areas, while in temperate regions it is predominantly caused by Candida species...Read More
Ten Pearls for Descemet's Membrane Detachment Repair
1. Embryology Understanding the embryological development of the cornea helps us appreciate the reasons for a Descemet's membrane (DM) detachment during surgery. After the lens vesicle separates from the surface epithelium, a wave of mesenchyme forms the primary corneal stroma. A second wave then forms the endothelium, which secretes the DM. The DM, hence, has a potential plane of separation f...Read More
Herpetic Eye Disease Study: All You Should Know
Herpes simplex virus (HSV) keratitis is the leading cause of corneal blindness in developed as well as developing countries. The ocular disease affects approximately 10 million people worldwide. Herpes viruses are a group of double-stranded DNA viruses with three subfamilies: alpha-, beta- and gamma- herpes viruses. HSV-1, HSV-2, and varicella-zoster virus (VZV) belong to the alpha-subfamily. HSV ...Read More