i-File: Stargardts Disease
Question A 35-year-old otherwise healthy female ( computer professional) presented with OU diminution noticed recently. BCVA OD 6/12 N6 and OS 6/18 N8. Anterior segment including IOP were normal in both eyes. Fundus examination revealed as depicted in the color fundus photo. What is the diagnosis( a differential is preferred) How do you manage this case Answer: The diagnosis is Stargardt’s Disease(SD)/Fundus flavimaculatus (FFM) Few Features: The onset of SD is generally in the first or second decade of life whereas FFM generally manifests after the 3 decades. The main presenting symptoms generally decrease in central vision. VISUAL ACUITY DOES NOT CORRELATE WITH FUNDUS APPEARANCE. Dyschromatopsia, nyctalopia, and visual field loss are generally not present. The earliest clinical sign is the loss of the foveolar reflex with symmetrical RPE alterations. Atrophy of fovea is generally marked by granularity, mottling, and presence of FLECKS(irregular-shaped yellow-white lesions with shapes

