Understanding Optic Disc Pallor- Shades of White
Introduction The optic nerve consists of approximately 1.2 million axons that arise from the retinal ganglion cells and acquire myelin sheath proximal to lamina cribrosa. These axons do not have the capacity to regenerate. The normal optic disc is pink in color due to the fact that light entering the optic disc is conducted along the transparent nerve fibers and they diffuse among columns of glial tissue and capillaries. When axons are damaged in optic atrophy, light is reflected from opaque glial cells and does not pass through the capillaries. In addition, the reduced capillary vascularity and loss of tissue causes visibility of opaque scleral lamina cause the disc to appear pale. Optic atrophy is the sequelae of progressive optic nerve disease that causes irreversible damage of ganglion cells and the retinogeniculate pathway. This degeneration along with gross reduction in capillaries results in loss of optic pathway conduction and pallor. Exploring the etiology of optic atrophy may

