Cornea

31–36 of 36 articles Page 4 of 4
  1. 24 min read

    Corneal Dystrophy: A Ready Reckoner for Postgraduates

    Corneal dystrophies are classically defined as a group of inherited disorders of the cornea which is bilateral, symmetric, slowly progressive, and not related to any environmental or systemic factors.1,2 Most of the corneal dystrophies begin in the early decades of life and progress gradually. The effect of these changes in some of the dystrophies may not be clinically apparent till the later years. The underlying basis of all corneal dystrophies are genetic mutations some of which have been mapped, while others are yet to be identified.1-3 Most of these mutations result in the transcription of aberrant proteins. These proteins are deposited in various corneal layers and give rise to the characteristic clinical features. The pace of deposition also determines the natural history of the corneal dystrophy. Corneal dystrophies were first reported by Groenouw in his article published in 1890.1 He described one patient with granular corneal dystrophy and another patient with macular corneal

  2. 21 min read

    Therapeutic Keratoplasty : A Comprehensive Review

    Microbial keratitis is a common vision-threatening disease that occurs in all parts of the world and is an important cause of avoidable corneal blindness. Medical therapy is considered a mainstay in the management of microbial keratitis, however, cases that worsen despite medical therapy or have perforation require surgical management1. Therapeutic keratoplasty is a surgical procedure whose primary purpose is to get rid of the infectious or non-infectious inflammatory tissue along with the restoration of the structural integrity of the eye (tectonic support)2. The surgical procedure, postoperative course, and chances of graft survival in therapeutic keratoplasty are different from optical keratoplasty as surgery is performed on an inflamed eye. Therapeutic keratoplasty could be Therapeutic Penetrating Keratoplasty(ThPK) Therapeutic lamellar keratoplasty- Deep Anterior Lamellar Keratoplasty(Th-DALK) Patch graft In therapeutic penetrating keratoplasty, a full-thickness button of the dise

  3. 40 min read

    Instruments used in Corneal Procedures and Surgeries

    Although tales and myths of ocular surgery and organ transplantation appear in numerous ancient texts, the earliest accounts of ophthalmic diseases were written as a treatise by Sushruta, in the 6th century BC. Sushruta described 76 eye diseases, out of which 51 required surgical treatment. In the western world, the concepts of corneal surgery date back to Greek physician Galen (130-200AD). The concepts to improve corneal clarity by surgery were developed over the next centuries and especially in the 17th and 18th centuries. But the major scientific progress and experimentation in the field of corneal surgeries happened in the 19th century. The progress in corneal surgery was hindered by a lack of understanding of immunology, asepsis, surgical procedures, and of course, the lack of proper instrumentation. Emmert Wolf wrote over a century ago, “A man is only as good as his tools.” Early surgeons were hampered by a lack of proper surgical instruments. Over the centuries, innumerable opht

  4. 8 min read

    Learn from the Masters : Viral Keratitis Decoded

    Viral Infections are more commonly encountered in individual practice than what presents in tertiary or referral eye care. Its presentation is myriad & baffling often a misdiagnosis as bacterial or fungal causing more harm. Also, with more choices on the availability of antivirals, individual practice varies. Here we discuss key presenting clinical features & know from the leading cornea experts their preferred treatment practices. Dr. Manisha Acharya is a practicing ophthalmologist hailing from Delhi. She received her MS degree (2003) from Jawaharlal Nehru Medical College, Aligarh following which she completed her fellowship at Dr. Shroff’s Charity Eye Hospital. She has also been trained at– Bascom Palmer Eye Institute, Miami, Florida, and LVPEI, Hyderabad. She is currently working as Senior Consultant, Department of Cornea and Refractive Surgery with Dr. Shroff’s Charity Eye Hospital, New Delhi. Apart from being a proficient corneal surgeon, Dr. Acharya is the Medical Director of the

  5. 14 min read

    Dry Eye – A Review

    INTRODUCTION: There are several definitions for dry eye available in world literature. The one that I prefer is the following: Dry eye is a disease in which there is a qualitative and /or quantitative decline in the tears accompanied by disorders of the ocular surface. The new definition proposed by the Dry Eye Workshop (DEWS) in 2006-07 states: Dry eye is a multifactorial disease of tear film & ocular surface resulting in symptoms of ocular discomfort, visual disturbance and tear film instability with potential damage to the ocular surface. This is associated with hyperosmolarity of the tear film and inflammation of ocular surface It is important that dry eye is recognized as a disease entity and not merely regarded as a nuisance. This definition also makes clear that one can have dry eye even in the presence of epiphora, as the quality of the tears may be inadequate to provide lubrication, with normal quantity of tear production. Also, even if the quality and quantity of tears is ini

  6. 13 min read

    Advanced Custom Ablation: New Technology for Better Quality of Vision

    LASIK is the most widely used technology for the correction of most spherocylindrical ametropias because of its safety and its predictability that leads to excellent outcomes for both the patient and the surgeon. Over the years there has been a progressive refinement of the technique. Customised correction of refractive errors using wavefront technology has revolutionised the way we plan and execute the treatment of refractive errors there are two specific reasons why customised treatment is transforming the entire LASIK arena. The first is that wavefront technology allows us to treat or not the only second order aberrations such as sphere and cylinder but also a higher order aberrations such as coma and spherical aberrations which exist in normal individuals as well as post refractive surgery patients. A major shift in the thought process of refractive surgery is that the LASIK surgeon now seeks to enhance vision beyond what nature itself and designed. With the advent of adaptive opti