Dr. Swapna Shanbhag

The Cornea Institute, LV. Prasad Eye Institute, Hyderabad, India

1 article

Dr. Swapna Shanbhag is a consultant ophthalmologist at the Cornea Institute, LV Prasad Eye Institute, Hyderabad, India. After finishing her Ophthalmology residency, Dr. Shanbhag completed a two year fellowship in Cornea and Anterior segment at LVPEI, Hyderabad and then pursued a two year research fellowship in Ocular Surface diseases (ocular chemical burns/SJS) at Massachusetts Eye and Ear affiliated to Harvard University, Boston, USA. Her research focuses on reducing the incidence and morbidity related to corneal blindness secondary to ocular surface disease such as corneal chemical burns and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). She is well-versed in the surgical management of ocular surface diseases and routinely performs surgeries such as SLET, Keratoprosthesis, mucous membrane grafts, and other forms of ocular surface reconstruction. She has published her research in international journals and has also presented at national and international meetings and has won awards for her research. She also serves on the editorial board of the Indian Journal of Ophthalmology.

  1. Articles 5 May 2021 25 min read

    Simple Limbal Epithelial Transplantation: A Review

    I. Introduction The cornea is lined by non-keratinized, stratified squamous epithelium. At the limbus, there is a gradual transition of these cells to non-keratinized, stratified columnar epithelial cells, along with mucin-secreting goblet cells, forming the conjunctival epithelium. The corneoscleral limbus lies between these two epithelia in a healthy eye. The limbus contains palisades of Vogt, the basal layer of which function as a repository for the corneal epithelial stem cells.(1, 2) These limbal epithelial stem cells (LESC’s) divide whenever the corneal epithelium is required to be replenished. As the stem cells divide, one of the daughter cells retains the primitive nature of the parent cell and functions to maintain the stem cell pool. The other daughter stem cell differentiates to acquire the physiological nature of a specific tissue, like the corneal epithelium. These cells are known as ‘transient amplifying cells’, which then divide and migrate centripetally, circumferential