Dr. Sharanya Abraham

Consultant, Department of Uvea , Sankara Nethralaya

1 article

Sharanya Abraham is a Consultant in the Uveitis department at Sankara Nethralaya, Chennai. She completed her ophthalmic training in Aravind Eye Hospitals, Madurai and Sankara Nethralaya, Chennai. She has presented at national conferences and published in national and international journals. She has an interest in intraocular infections.

  1. Articles 30 Nov 2021 25 min read

    Ocular Manifestations of HIV

    Human immunodeficiency virus (HIV) disease is a pandemic of global concern, not only due to serious health issues affecting all organs of the body but also due to its huge economic burden.(1) The diagnosis is often associated with social stigma that includes changing sexual practices, lack of availability of a vaccine and the chronicity of the disease requiring lifelong treatment.(2) The disease runs a severe course, involving multiple organs. Ocular lesions are varied and can affect any structure, usually in the late phase of HIV infection. Rarely, these lesions can be the presenting manifestations of the disease. While a variety of cell types may be infected by HIV, the immunologic hallmark is the selective loss of the CD4+ T cells. CD4 is a cell surface marker that identi?es the helper/inducer subset of T cells. During the initial phases of infection, a majority of patients remain asymptomatic. With a decrease in the CD4+ T cell count (< 500 cells/µL) the immune system shows evidenc

    Dr. Sharanya Abraham