Dr. Janani Madhuravasal Krishnan

Post-doctoral fellow, MED-Int Med-Digestive Diseases, University of Cincinnati, US

1 article

Janani received her Bachelors in Microbiology (2007) with gold medal and Masters of Science (2010) degrees in the field of Microbiology and Medical Laboratory technology from BITS Pilani, India. She then worked at Medical Research Foundation, Sankara Nethralaya as a junior scientist and simultaneously pursued her PhD in Biomedical Science under BITS PILANI. Her dissertation study was focused on molecular identification and genotyping of Epstein Barr Virus in pediatric populations. Janani served as a Senior Scientist at the Sankara Nethralaya Referral Laboratory, India after her doctorate (2016) and gained in-depth knowledge on the clinical diagnosis of infectious agents causing ocular and respiratory infections. She was awarded a Research Associate Fellowship by ICMR in 2019 to examine novel adjuvants involved in antifibrogenic activity. She has ten first author international publications and has co-authored 5 international publication and 16 case reports to date. She also has ten years of teaching experience in microbiology training undergraduates and conducting short term research projects with trainees. To advance her skills and expertise in virology, she joined the Division of Digestive Diseases at the University of Cincinnati College of Medicine as a post-doctoral fellow in April 2021. Janani is working on a NIDA-funded R61 and NIDA supplement on several projects, including In vitro studies of the impact of drugs of abuse on HIV disease progression and In vitro studies of the impact of SARS-CoV-2 infection and drugs of abuse on cellular gene expression and markers of HIV disease progression.

  1. Articles 22 Mar 2022 5 min read

    Polymerase Chain Reaction in Ocular Infections

    Newer technological progressions in molecular science have paved the way for a better understanding of infectious diseases. DNA-based molecular diagnostic techniques which are specific, sensitive, and rapid in the identification of the pathogen in the clinical specimen has been developed extensively over the past decades The rapid identi?cation of speci?c infectious agents is very important for the diagnosis of an ocular infection because the course of treatment and disease prognosis could be different from non-infectious diseases. Despite the availability of a wide variety of antimicrobial agents to treat these infections, specific treatment is delayed due to the inability to identify ocular pathogens quickly and accurately. PCR has emerged as an essential powerful rapid laboratory diagnostic technique complement the conventional gold standard “culture “, with special reference to difficult to grow or slow-growing microbial agents like viruses, Mycobacterium tuberculosis, anaerobic ba