Dr. Eli Pradhan

Medical Retina Consultant, Tilganga institute of Ophthalmology, Kathmandu, Nepal

1 article

Dr. Eli Pradhan completed MBBS and was awarded Gold Medal while completing MS (ophthalmology) from Tribhuvan University Teaching Hospital. She cleared MRCS Ophthalmology Royal College of surgeons of Edinburgh, UK and completed fellowship in Medical Retina from TIO, Kath, Nepal. She is currently working as a medical Retina consultant at Tilganga Institute of Ophthalmology, Kath, Nepal, and serving the Nepalese Journal of Ophthalmology as Editor in Chief. She is currently the President of Nepal Vitreo Retina Society ( NVRS ) and a committee member, Women in Ophthalmology, Asia Pacific Academy of Ophthalmology. Dr. Pradhan is a scientific chairman, SAARC Ophthalmology, SAO, and country representative in Asia Pacific Ocular Trauma society ( APOTS)

  1. Articles 25 Oct 2021 8 min read

    Anti-VEGFs made Easy for the Postgraduates

    The retina is a highly metabolic tissue and needs a constant high supply of oxygen. Insult to either choroidal or retinal vasculature can lead to a hypoxic state. Throughout the years, neovascularization has been seen to occur in areas neighboring such hypoxic areas. In 1989, this hypoxia-inducible and diffusible factor was discovered to be Vascular Endothelial Growth Factor (VEGF), initially coined as Vascular Permeability Factor (VPF). VEGF was found to be answerable for many types of retinopathies and the increased vascular permeability seen in them. VEGF is a heparin-binding dimeric glycoprotein with di-sulfide-linked A and B subunits. VEGF has been found to be produced by many cell types in the retina including vascular endothelial cells, retinal pigment epithelium, pericytes, Muller cells, retinal neurons, and astrocytes. It is necessary for the survival of retinal cells; prenatally for proper embryological development of the retina as well as postnatally for preserving adult mic

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